90914-81-1

Basic information

• Product Name: 4'-BROMO-3'-METHYLACETANILIDE
• Synonyms: 4''-BROMO-3''-METHYLACETANILIDE,98%;N-Acetyl-4-bromo-m-toluidine;N-Acetyl 4-Bromo-3-methylaniline;3-Methyl-4-bromo-N-acetylaniline;4'-Bromo-m-acetotoluidide;SALOR-INT L168106-1EA;4'-BROMO-3'-METHYLACETANILIDE;4-BROMO-3-METHYLACETANILIDE
• CAS NO: 90914-81-1
• Molecular Formula: C₉H₁₀BrNO
• Molecular Weight: 228.09
• Product Categories: Anilines, Amides & Amines;Bromine Compounds
• Mol File: 90914-81-1.mol
• Article Data: 15

Chemical Properties

• Melting Point: 102-104°C
• Boiling Point: 351℃
• Flash Point: 166℃
• Appearance: /
• Density: 1.471
• Vapor Pressure: 4.33E-05mmHg at 25°C
• Refractive Index: 1.6
• Storage Temp.: Room temperature.
• PKA: 14.25±0.70(Predicted)
• CAS DataBase Reference: 4'-BROMO-3'-METHYLACETANILIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-BROMO-3'-METHYLACETANILIDE(90914-81-1)
• EPA Substance Registry System: 4'-BROMO-3'-METHYLACETANILIDE(90914-81-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 90914-81-1(Hazardous Substances Data)

Usage

General Description

4'-Bromo-3'-Methylacetanilide is a chemical compound that is commonly used in the pharmaceutical industry for the production of various drugs. It is a derivative of acetanilide, which is known for its analgesic and fever-reducing properties. The incorporation of a bromine and a methyl group into the acetanilide molecule allows for the modification of its biological activity and pharmacological properties. 4'-BROMO-3'-METHYLACETANILIDE is often used as an intermediate in the synthesis of drugs and can also be employed in research and development of new pharmaceuticals. Its chemical structure and properties make it a valuable component in the production of a wide range of pharmaceutical products.

InChI:InChI=1/C9H10BrNO/c1-6-5-8(11-7(2)12)3-4-9(6)10/h3-5H,1-2H3,(H,11,12)

Upstream product

• 537-92-8 3-Methylacetanilide 
• 108-44-1 1-amino-3-methylbenzene 
• 65854-92-4 N-(2-bromophenyl)-2,2-dimethylpropanamide 
• 615-36-1 2-bromoaniline 
• 6933-10-4 amino-5-bromo-2-toluene 
• 108-24-7 acetic anhydride 

Downstream Products

• 716-65-4 N-(4-bromo-5-methyl-2-nitrophenyl)acetamide 
• 22921-67-1 5-acetylamino-2-bromobenzoic acid 
• 854624-54-7 4-bromo-3-methyl-2-nitro-aniline 
• 116779-85-2 2,3,6-tribromo-toluene 
• 13194-73-5 3,5-dibromo-4-methylaniline 
• 69321-60-4 2,6-dibromotoluene 
• 140373-62-2 2,5-dibromo-4-methyl-aniline 
• 1263376-95-9 3,6-dibromo-2-methyl-aniline 
• 219310-40-4 1,4-dibromo-2-methyl-5-nitrobenzene 
• 101581-06-0 1,3-dibromo-2-methyl-5-nitrobenzene 
• 392318-87-5 2,6-dibromo-3,5-dinitro-toluene 
• 537-92-8 3-Methylacetanilide 
• 1374606-55-9 N-(4-bromo-5-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide 

Relevant articles and documents

TERBIUM AND DYSPROSIUM COMPLEXES WITH OPTIMISED ANTENNA, USED AS LUMINESCENT MARKERS

The present invention relates to luminescent lanthanide complexes comprising a chelating agent, formed of a macrocycle or ligand, complexing a lanthanide ion, as well as corresponding chelating agents and a process for detecting a biomolecule using said l

Combining Eosin y with Selectfluor: A Regioselective Brominating System for Para-Bromination of Aniline Derivatives

A mild, metal-free, and absolutely para-selective bromination of aniline derivatives has been developed in excellent yields, wherein the organic dye Eosin Y is employed as the bromine source in company with Selectfluor. Neither air nor moisture sensitive, this facile reaction proceeds smoothly at room temperature and completes within a short time. Mechanistic studies indicate a radical pathway; therefore, the existence of an in situ generated brominating reagent, "Selectbrom", is postulated, which may reasonably account for the unique regioselectivity for the para-bromination of N-acyl- as well as N-sulfonylanilines.

Synthesis and characterization of the first inhibitor of: N -acylphosphatidylethanolamine phospholipase D (NAPE-PLD)

N-Acylphosphatidylethanolamine phospholipase D (NAPE-PLD) is a membrane-associated zinc enzyme that catalyzes the hydrolysis of N-acylphosphatidylethanolamines (NAPEs) into fatty acid ethanolamides (FAEs). Here, we describe the identification of the first small-molecule NAPE-PLD inhibitor, the quinazoline sulfonamide derivative 2,4-dioxo-N-[4-(4-pyridyl)phenyl]-1H-quinazoline-6-sulfonamide, ARN19874.