90915-18-7 Usage
General Description
1H-Benzimidazole-5-carboxylic acid, 1,2-dimethyl-(9CI) is a chemical compound with the molecular formula C10H10N2O2. It is a derivative of benzimidazole and contains a carboxylic acid and two methyl groups. 1H-Benzimidazole-5-carboxylicacid,1,2-dimethyl-(9CI) has potential applications in the pharmaceutical industry, as benzimidazoles are known for their diverse biological activities, including anti-cancer, anti-viral, and anti-inflammatory properties. The presence of a carboxylic acid group also suggests that it may have potential as a building block for the synthesis of other organic compounds. Further research and testing are necessary to fully understand the potential uses and properties of 1H-Benzimidazole-5-carboxylic acid, 1,2-dimethyl-(9CI).
Check Digit Verification of cas no
The CAS Registry Mumber 90915-18-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,9,1 and 5 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 90915-18:
(7*9)+(6*0)+(5*9)+(4*1)+(3*5)+(2*1)+(1*8)=137
137 % 10 = 7
So 90915-18-7 is a valid CAS Registry Number.
90915-18-7Relevant articles and documents
Total synthesis of hypermodified epothilone analogs with potent in vitro antitumor activity
Kuzniewski, Christian N.,Gertsch, Jurg,Wartmann, Markus,Altmann, Karl-Heinz
supporting information; experimental part, p. 1183 - 1186 (2009/04/06)
The convergent total synthesis of hypermodified epothilone analogs 1 and 2 has been achieved with the stereoselective cyclopropanation of allylic alcohol 17 and ring-closing olefin metathesis with diene 22 as the key steps. In spite of significant structural differences between these analogs and the natural epothilone scaffold, 1 and 2 are potent inducers of tubulin polymerization and inhibit the growth of human cancer cells in vitro with sub-nM IC50 values.