90916-29-3

Usage

Uses

Used in Pharmaceutical Industry:
N-Allyloxycarbonyl-2-nitrobenzenesulfonamide is used as a reagent for the total synthesis of (-)-lepistine, a compound with potential applications in drug development and medicinal chemistry. Its role in the synthesis process is crucial for the production of this alkaloid, which may exhibit therapeutic properties and contribute to the discovery of new pharmaceutical agents.

InChI:InChI=1/C10H10N2O6S/c1-2-7-18-10(13)11-19(16,17)9-6-4-3-5-8(9)12(14)15/h2-6H,1,7H2,(H,11,13)

Upstream product

• 5455-59-4 2-Nitrobenzenesulfonamide 
• 2937-50-0 Allyl chloroformate 

Downstream Products

• 245364-53-8 C₁₇H₂₄N₂O₆S 
• 245364-54-9 C₁₅H₁₈N₂O₈S 
• 943601-34-1 {4-[4-(tetrahydropyran-2-yloxymethyl)benzoyl]benzyl}nosylcarbamic acid allyl ester 
• 943601-49-8 C₃₂H₃₉F₃N₄O₉S 
• 943601-35-2 {4-[4-(hydroxymethyl)benzoyl]benzyl}nosylcarbamic acid allyl ester 
• 1609184-06-6 (S)-N-(5-(N-allyloxycarbonyl-2-nitrobenzenesulfonamido)-2-methylenepentyl)-N-glycidyl-2-nitrobenzenesulfonamide 
• 1609184-07-7 (S)-N-glycidyl-N-(2-methylene-5-(2-nitrobenzenesulfonamido)pentyl)-2-nitrobenzenesulfonamide 
• 1609184-08-8 (R)-7-methylene-1,5-bis((2-nitrobenzene)sulfonyl)-1,5-diazecan-3-ol 
• 1609184-22-6 (S)-7-methylene-3-(2-nitrophenoxy)-1-(2-nitrobenzenesulfonyl)-1,5-diazecane 
• 1609184-09-9 (1R,7S)-3,9-bis(2-nitrobenzenesulfonyl)-11-oxa-3,9-diazabicyclo[5.3.1]undecan-7-ol 
• 1609184-10-2 (R)-3,9-bis(2-nitrobenzenesulfonyl)-11-oxa-3,9-diazabicyclo[5.3.1]undec-7-ene 

Relevant academic research and scientific papers

Intramolecular Aminoazidation of Unactivated Terminal Alkenes by Palladium-Catalyzed Reactions with Hydrogen Peroxide as the Oxidant

The palladium-catalyzed aminoazidation of aminoalkenes yielding azidomethyl-substituted nitrogen-containing heterocycles was developed. The procedure requires oxidative conditions and occurs at room temperature in the presence of hydrogen peroxide and NaN3 as the azide source. These conditions provide selective exo-cyclization/azidation of the carbon-carbon double bond, furnishing a versatile approach toward five-, six-, and seven-membered heterocyclic rings.

HEAVY-NITROGENIZED NITROBENZENESULFONAMIDE, ITS DERIVATIVE AND PRODUCTION METHOD THEREOF

PROBLEM TO BE SOLVED: To provide a heavy-nitrogenized nitrobenzenesulfonamide derivative and an efficient production method thereof. SOLUTION: The heavy-nitrogenized nitrobenzenesulfonamide compound is represented by general formula [2]. An amino group of

N-carboalkoxy-2-nitrobenzenesulfonamides: A practical preparation of N- Boc-, N-Alloc-, and N-Cbz-protected primary amines

N-Carboalkoxy-2-nitrobenzenesulfonamides, readily prepared by acylation of 2-nitrobenzenesulfonamide (o-NsNH2), can be alkylated by either conventional or Mitsunobu protocols. Since the o-nosyl group can be deprotected under mild conditions, a variety of N-carboalkoxy derivatives of primary amines may be prepared in excellent yields from the corresponding alcohols and/or halides. In addition, allyloxycarbonyl (Alloc), t- butoxycarbonyl (t-Boc), and benzyloxycarbonyl (Cbz) groups can be deprotected in the presence of the o-nosyl group, allowing the resultant N-alkylated 2- nitrobenzenesulfonamides to be used for further preparation of secondary amines.