90924-43-9

Basic information

• Product Name: 6-Methoxy-1H-indole-3-carboxylic acid
• Synonyms: 6-METHOXY-1H-INDOLE-3-CARBOXYLIC ACID;6-METHOXY-2,3-DIHYDRO-1H-INDOLE-3-CARBOXYLIC ACID;6-METHOXYINDOLE-3-CARBOXYLIC ACID;1H-Indole-3-carboxylicacid, 6-Methoxy-;6-Methoxy-3-indolecarboxylic Acid;Indole-3-carboxylic acid, 6-methoxy-
• CAS NO: 90924-43-9
• Molecular Formula: C₁₀H₉NO₃
• Molecular Weight: 191.18
• Product Categories: pharmacetical;Heterocycles series;Indoline & Oxindole
• Mol File: 90924-43-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 447.575 °C at 760 mmHg
• Flash Point: 224.486 °C
• Appearance: /
• Density: 1.381 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.677
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-Methoxy-1H-indole-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Methoxy-1H-indole-3-carboxylic acid(90924-43-9)
• EPA Substance Registry System: 6-Methoxy-1H-indole-3-carboxylic acid(90924-43-9)

Safety Data

• Hazardous Substances Data: 90924-43-9(Hazardous Substances Data)

Usage

General Description

6-Methoxy-1H-indole-3-carboxylic acid is a chemical compound with the molecular formula C11H9NO4. It is a derivative of indole, a heterocyclic aromatic organic compound. 6-Methoxy-1H-indole-3-carboxylic acid is a carboxylic acid, meaning it contains a carboxyl group, and it also contains a methoxy group. It has potential applications in the field of medicinal chemistry, as it is a precursor to biologically active molecules such as pharmaceutical drugs. Research on this compound and its derivatives has focused on their potential anti-inflammatory and anticancer properties. Additionally, it has been studied for its potential use in the synthesis of natural products and other bioactive compounds.

InChI:InChI=1/C10H9NO3/c1-14-6-2-3-7-8(10(12)13)5-11-9(7)4-6/h2-5,11H,1H3,(H,12,13)

Upstream product

• 1016163-40-8 6-methoxy-3-trichloroacetylindole 
• 3189-13-7 6-methoxylindole 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 1396743-90-0 C₂₀H₂₀N₄O₄S 
• 1396743-88-6 C₁₈H₁₆N₄O₂S 
• 1396744-24-3 C₂₀H₂₂N₄O₅S 
• 1396744-22-1 C₁₈H₁₈N₄O₃S 
• 88612-61-7 ethyl 6-methoxyindole-3-carboxylate 
• 1016163-17-9 6-methoxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]methyl}-2-methylpropyl]-1H-indole-3-carboxamide 

Relevant articles and documents

Synthesis and in vitro opioid receptor functional antagonism of analogues of the selective kappa opioid receptor antagonist (3R)-7-hydroxy-N-((1S)-1- {[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl) -1,2,3,4-tetrahydro-3-is

In previous structure-activity relationship (SAR) studies, we identified (3R)-7-hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1- piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3- isoquinolinecarboxamide (JDTic, 1) as the first poten

BENZOFUSED HETEROARYL AMIDE DERIVATIVES OF THIENOPYRIDINES USEFUL AS THERAPEUTIC AGENTS, PHARMACEUTICAL COMPOSITIONS INCLUDING THE SAME, AND METHODS FOR THEIR USE

The invention relates to compounds represented by the formula I and to prodrugs or metabolites thereof, or pharmaceutically acceptable salts or solvates of said compounds, said prodrugs, and said metabolites, wherein Z, Y, R11 and R14, R15, R16, and R17 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula I.