90929-77-4

Basic information

• Product Name: 1-(2-hydroxyethyl)-7-azaindole
• Synonyms: 1-(2-hydroxyethyl)-7-azaindole
• CAS NO: 90929-77-4
• Molecular Formula: C₉H₁₀N₂O
• Molecular Weight: 162.1885
• Mol File: 90929-77-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(2-hydroxyethyl)-7-azaindole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-hydroxyethyl)-7-azaindole(90929-77-4)
• EPA Substance Registry System: 1-(2-hydroxyethyl)-7-azaindole(90929-77-4)

Safety Data

• Hazardous Substances Data: 90929-77-4(Hazardous Substances Data)

Upstream product

• 271-63-6 7-Azaindole 
• 540-51-2 2-bromoethanol 
• 172647-94-8 methyl 7-azaindol-1-acetate 
• 75-21-8 oxirane 
• 74420-15-8 3-bromo-1H-pyrrolo[2,3-b]pyridine 

Downstream Products

• 1562526-67-3 2-(2-(1H-pyrrolo[2,3-b]pyridin-1-yl)ethyl)-4-(benzyloxymethyl)-6-bromo-1,2,4-triazine-3,5(2H,4H)-dione 
• 1562526-70-8 2-(2-(1H-pyrrolo[2,3-b]pyridin-1-yl)ethyl)-6-(benzyloxy)-4-(benzyloxymethyl)-1,2,4-triazine-3,5(2H,4H)-dione 

Relevant articles and documents

Cu(I)-Catalyzed Intramolecular Tandem Cyclization of N-Indole-Tethered Cyclopropenes: Synthesis of Functionalized Hydrogenated Diazabenzo[ a]cyclopenta[ cd]azulene Derivatives

A Cu(I)-catalyzed [3 + 2] intramolecular cycloaddition reaction of N-indole-tethered cyclopropenes is presented in this paper. This reaction starts from the formation of ?-allyl cationic intermediate or its resonance-stabilized metal carbenoid intermediate upon activation of cyclopropene with Cu(I) catalyst and a Friedel-Crafts-type cyclization to give functionalized hydrogenated diazabenzo[a]cyclopenta[cd]azulenes in good to excellent yields along with moderate to good dr values. The asymmetric variant of this cycloaddition reaction can be realized, giving the desired products with moderate ee values.

Reactivity of 1H-Pyrrolopyridine. II. Synthesis of 3-(β-Haloethyl)-7-azaindole

The preparation of 3-(2-chloroethyl)-7-azaindole and 3-(2-bromoethyl)-7-azaindole are described.