909415-01-6Relevant academic research and scientific papers
Asymmetric synthesis of (2S)-1-(3,4-dihydroxyphenoxy)-3-(3,′4′- dimethoxyphenoxy) ethylamino-2-propanol hydrochloride (RO363)
Narsaiah, Akkirala Venkat
, p. 1897 - 1901 (2007/10/03)
Enantiomerically pure (S)-RO363 was synthesized by using (R,R) Salen Co(III) complex for the resolution of terminal epoxide. The hydrolytic kinetic resolution process was carried out at room temperature in excellent enantioselectivity. The method can be a
