909563-41-3Relevant academic research and scientific papers
Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors
Nagashima, Shinya,Hondo, Takeshi,Nagata, Hiroshi,Ogiyama, Takashi,Maeda, Jun,Hoshii, Hiroaki,Kontani, Toru,Kuromitsu, Sadao,Ohga, Keiko,Orita, Masaya,Ohno, Kazuki,Moritomo, Ayako,Shiozuka, Koichi,Furutani, Masako,Takeuchi, Makoto,Ohta, Mitsuaki,Tsukamoto, Shin-ichi
experimental part, p. 6926 - 6936 (2009/12/24)
Signal transducers and activators of transcription 6 (STAT6) is an important transcription factor in interleukin (IL)-4 signaling pathway and a key regulator of the type 2 helper T (Th2) cell immune response. Therefore, STAT6 may be an excellent therapeut
