909567-48-2Relevant academic research and scientific papers
SUBSTITUTED AMINO ALCOHOLS
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Page/Page column 27, (2009/04/24)
Disclosed herein are substituted amino alcohol anti-mycobacterial agents and/or chelation therapy agents of Formula I, process of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.
Enantioselective synthesis of (S,S)-ethambutol using proline-catalyzed asymmetric α-aminooxylation and α-amination
Kotkar, Shriram P.,Sudalai, Arumugam
, p. 1738 - 1742 (2007/10/03)
An efficient enantioselective synthesis of (S,S)-ethambutol, a tuberculostatic antibiotic, has been achieved in 99% ee via both proline-catalyzed α-aminooxylation and α-amination of n-butyraldehyde as the key step.
