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Upstream product

• 554-95-0 benzene-1,3,5-tricarboxylic acid 
• 22348-32-9 (S)-diphenylprolinol 
• 4422-95-1 1,3,5-benzene tris(carbonyl chloride) 

Relevant academic research and scientific papers

Highly enantioselective borane reduction of prochiral ketones catalyzed by C3-symmetric tripodal β-hydroxy amides

The asymmetric borane reduction of prochiral ketones with a series of easily constructed chiral C3-symmetric tripodal tris(β- hydroxyamide) ligands was investigated. The borane complex of chiral ligand 1,1′,″,-(1,3,5-benzenetricarbonyl)-tris[(2S)-α, α-diphenyl-2-pyrrolidinemethanol] (1h) was found to be an efficient catalyst in asymmetric borane reduction of prochiral ketones and excellent enantioselectivities were obtained with both electron-deficient and electron-rich prochiral ketones (up to 97% ee). Georg Thieme Verlag Stuttgart.