90976-97-9

Upstream product

• 93379-40-9 2-hydroxymethyl-cyclohexanecarboxylic acid 
• 87-41-2 2-benzofuran-1(3H)-one 
• 13169-51-2 2-(chloromethyl)benzamide 
• 55741-02-1 o-(N,N-Diethyl-aminomethyl)-benzoesaeure 
• 6939-71-5 hexahydro-isobenzo[c]furan-1-one 
• 64-17-5 ethanol 
• 87-24-1 ethyl 2-methylbenzoate 
• 20924-53-2 ethyl <(2-carbethoxybenzyl)oxy>acetate 
• 118-90-1 ortho-methylbenzoic acid 

Downstream Products

• 92984-25-3 methyl bicyclo<4.1.0>heptanecarboxylate 
• 10479-74-0 ((1S,2R)-2-Chloromethyl-cyclohexyl)-methanol 

Relevant academic research and scientific papers

Sequenced Reactions with Samarium(II) Iodide. Sequential Intermolecular Carbonyl Addition/Intramolecular Nucleophilic Acyl Substitution for the Preparation of Seven-, Eight-, and Nine-Membered Carbocycles

Samarium(II) iodide has been employed to promote a tandem intermolecular carbonyl addition/ intramolecular nucleophilic acyl substitution sequence, generating seven-through nine-membered monocyclic, bicyclic, and tricyclic ring systems with good yields an

Substituent Effects on Hydrogenation of Aromatic Rings: Hydrogenation vs. Hydrogenolysis in Cyclic Analogues of Benzyl Ethers.

Carbalkoxy substituents are shown to retard the hydrogenation of aromatic rings over Rh/C catalyst.Hydrogenolysis predominates with acyclic (benzyloxy)acetates over this catalyst, but both hydrogenation and hydrogenolysis become sluggish with 2-isochroman-4-ones (1).However, phthalides may be cleanly hydrogenated in moderate to excellent yields without significant hydrogenolysis.Placing a benzyl ether in a ring system appears to greatly retard hydrogenolysis relative to the acyclic analogues.