909804-89-3Relevant academic research and scientific papers
Crystallisation induced asymmetric transformation (CIAT) in the synthesis of furoylalanines and furylcarbinols
Jakubec, Pavol,Berkes, Dusan,Siska, Richard,Gardianova, Maria,Povazanec, Frantisek
, p. 1629 - 1637 (2007/10/03)
A new synthesis of enantiomerically highly enriched N-substituted furoylalanines has been developed. This process involves the combination of crystallisation induced asymmetric transformation (CIAT) and a conjugate addition of N-nucleophiles to furoylacrylic acids. Further transformations to furoylalanines and substituted furylcarbinols are also described.
