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909854-52-0

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909854-52-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 909854-52-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,9,8,5 and 4 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 909854-52:
(8*9)+(7*0)+(6*9)+(5*8)+(4*5)+(3*4)+(2*5)+(1*2)=210
210 % 10 = 0
So 909854-52-0 is a valid CAS Registry Number.

909854-52-0Upstream product

909854-52-0Downstream Products

909854-52-0Relevant articles and documents

Discovery of the first nonpeptidic, Small-molecule, highly selective somatostatin receptor subtype 5 antagonists: A chemogenomics approach

Martin, Rainer E.,Green, Luke G.,Guba, Wolfgang,Kratochwil, Nicole,Christ, Andreas

, p. 6291 - 6294 (2008/03/30)

We disclose the first selective, nonpeptidic, small-molecule somatostatin receptor subtype 5 (SST5R) antagonists that were identified by a chemogenomics approach based on the analysis of the homology of amino acids defining the putative consensus drug binding site of SST5R. With this strategy, opioid, histamine, dopamine, and serotonine receptors were identified as the closest neighbors of SST5R. The H1 antagonist astemizole was chosen as a seed structure and subsequently transformed into a SST5 receptor antagonist with nanomolar binding affinity devoid of the original target activity.

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