910032-21-2

Basic information

• Product Name: 2-(2-bromoethoxy)-1-chloro-4-methyl-benzene
• CAS NO: 910032-21-2
• Molecular Formula: C₉H₁₀BrClO
• Molecular Weight: 249.5321
• Mol File: 910032-21-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 299.6°C at 760 mmHg
• Flash Point: 135°C
• Density: 1.456g/cm³
• Vapor Pressure: 0.0021mmHg at 25°C
• Refractive Index: 1.555
• CAS DataBase Reference: 2-(2-bromoethoxy)-1-chloro-4-methyl-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-bromoethoxy)-1-chloro-4-methyl-benzene(910032-21-2)
• EPA Substance Registry System: 2-(2-bromoethoxy)-1-chloro-4-methyl-benzene(910032-21-2)

Safety Data

• Hazardous Substances Data: 910032-21-2(Hazardous Substances Data)

Usage

Structure

Benzene derivative with a bromoethoxy group, a chloro group, and a methyl group

Physical state

Clear, colorless to pale yellow liquid

Solubility

Soluble in organic solvents

Odor

Characteristic odor

Usage

Used in various organic synthesis and chemical reactions as a starting material or intermediate

Primary applications

Manufacturing of pharmaceuticals, agrochemicals, and specialty chemicals

Safety precautions

Handle with care and follow proper safety procedures when working with it

Upstream product

• 615-74-7 2-chloro-5-methylphenol 
• 60222-55-1 2-(2-chloro-5-methyl-phenoxy)-ethanol 

Downstream Products

• 1430210-48-2 2-((2-(2-chloro-5-methylphenoxy)ethyl)thio)-5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluoro phenyl)-1H-imidazole 
• 40987-20-0 C₁₃H₁₉ClN₂O 

Relevant articles and documents

Design, synthesis and anticonvulsant-analgesic activity of new N-[(phenoxy)alkyl]- and N-[(phenoxy)ethoxyethyl]aminoalkanols

New derivatives of N-[(phenoxy)alkyl]- and N-[(phenoxy)ethoxyethyl]aminoalkanols have been synthesized and evaluated for their anticonvulsant activity in maximal electroshock (MES), maximal electroshock seizure threshold (MEST), and pentylenetetrazol (PTZ) tests. Their neurotoxicity was evaluated via rotarod and chimney tests. The compounds exhibiting the most beneficial activity and protection indices were evaluated for analgesic activity using the formalin test for neurogenic pain. They were also evaluated for their influence on cytotoxic activity using in vitro cellular models (HepG2 and CRL-2534 cell lines). Experiments performed using MTT and neutral red cytotoxicity assays showed that all evaluated compounds were safe for normal, glial cells (astrocytes) and did not induce hepatotoxic effects. Based on the results from the in vitro studies, the safety of the evaluated compounds was inferred. The most promising compound in this research was 1-{2-[2-(2,3-dimethylphenoxy)ethoxy]ethyl}piperidin-3-ol hydrochloride. Additionally, in silico metabolism prediction for the compound has been performed.