910212-45-2Relevant academic research and scientific papers
New reactivity and structural insights of alkali-metal-mediated alumination in directed ortho-alumination of a tertiary aromatic amide
Garcia-Alvarez, Joaquin,Graham, David V.,Kennedy, Alan R.,Mulvey, Robert E.,Weatherstone, Susan
, p. 3208 - 3210 (2006)
The first reported sodium alkyl(TMP)aluminate reagent to be synthesised and crystallographically characterised, [TMEDA·Na(μ-TMP)(μ- iBu)Al(iBu)2], reacts as an amido base towards phenylacetylene to form crystalline [(TMEDA)2·Na(μ-CCPh) (μ-iBu)Al(iBu)2]; whereas the congeneric TMEDA-stabilised lithium (TMP)aluminate exhibits dual alkyl/amido basicity in its reaction with N,N-diisopropylbenzamide to form a novel heterobimetallic- heterotrianionic crystalline complex [{PhC(=O)N(iPr) 2}·Li{2-[1-C(=O)N(iPr)2]C 6H4}{Me2NCH2CH2N(Me) CH2}Al(iBu)2], which, in addition to having an ortho-deprotonated benzamide ligand, also contains a methyl-deprotonated TMEDA ligand and a neutral benzamide molecule ligated to lithium. The Royal Society of Chemistry 2006.
