910220-80-3

Basic information

• Product Name: 4'-Trifluoromethyl-biphenyl-4-carboxylic acid methyl-[(S)-1-((R)-3-methylamino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-amide
• CAS NO: 910220-80-3
• Molecular Weight: 474.526
• Mol File: 910220-80-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4'-Trifluoromethyl-biphenyl-4-carboxylic acid methyl-[(S)-1-((R)-3-methylamino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-Trifluoromethyl-biphenyl-4-carboxylic acid methyl-[(S)-1-((R)-3-methylamino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-amide(910220-80-3)
• EPA Substance Registry System: 4'-Trifluoromethyl-biphenyl-4-carboxylic acid methyl-[(S)-1-((R)-3-methylamino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-amide(910220-80-3)

Safety Data

• Hazardous Substances Data: 910220-80-3(Hazardous Substances Data)

Upstream product

• 392338-15-7 tert-butyl [(3R)-pyrrolidin-3-yl]methylcarbamate 
• 181146-88-3 4'-(trifluoromethyl)-4-biphenylcarbonyl chloride 
• 169749-99-9 (3S)-(-)-1-benzyl-3-(methylamino)pyrrolidine 
• 762285-67-6 4'-Trifluoromethyl-biphenyl-4-carboxylic acid ((S)-1-benzyl-pyrrolidin-3-yl)-methyl-amide 
• 762285-68-7 4'-Trifluoromethyl-biphenyl-4-carboxylic acid methyl-(S)-pyrrolidin-3-yl-amide 
• 910220-79-0 3-(tert-butoxycarbonyl-methyl-amino)-pyrrolidine-1-carboxylic acid 4-nitro-phenyl ester 

Relevant articles and documents

Synthesis and structure-activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 1

The design, synthesis, and SAR of a series of retro bis-aminopyrrolidine ureas are described. Compounds from this series exhibited potent binding affinity and functional activity at MCH-R1, and good oral bioavailability in rat.