910249-74-0Relevant academic research and scientific papers
Synthesis and antibacterial activity of C12 des-methyl ketolides
Lin, Xiaodong,Rico, Alice C.,Chu, Daniel T.,Carroll, Georgia L.,Barker, Lynn,Shawar, Ribhi,Desai, Manoj C.,Plattner, Jacob J.
, p. 4692 - 4696 (2007/10/03)
Synthesis of C12 des-methyl ketolide is developed featuring an intramolecular epoxide formation/elimination process to establish the C12 stereocenter. These ketolides are potent against several key respiratory pathogens, including er
