91029-16-2Relevant academic research and scientific papers
BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS GNRH ANTAGONISTS
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Page/Page column 33, (2008/06/13)
A subject of the present application is new benzimidazole derivatives of formula in which A, Y, R1, R2, R3 and R4 represent different variable groups. These products have an antagonist activity of GnRH (Gonadotropin-Releasing Hormone). The invention also relates to pharmaceutical compositions containing said products and their use for the preparation of a medicament.
SYNTHESIS OF FUNCTIONALLY SUBSTITUTED PYRIDINES AND DIPYRIDYL-SUBSTITUTED COMPOUNDS WITH THE AID OF LOW-VALENCE COMPOLEXES
Selimov, F. A.,Khafizov, V. R.,Dzhemilev, U. M.
, p. 290 - 295 (2007/10/02)
The possibility of the preparation of oxygen, nitrogen, and sulfur-containing pyridines and dipyridyl-substituted compounds by the cyclocotrimerization of substituted propionitriles with acetylene under the influence of a Co(2-ethylhexanoate)2-Al(C2H5)3 catalyst was demonstrated.It was established that the nature of the heteroatom in substituted propionitriles has virtually no effect on the direction of the reaction.
