910330-24-4Relevant academic research and scientific papers
THERAPEUTIC AGENTS
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Paragraph 0139, (2014/11/11)
The invention provides well-defined compounds that are either EP2 agonists, EP4 agonists, or mixed EP2/EP4 agonist. The compounds are useful for treating a variety of pathological conditions associated with acti
Novel ligands for the human histamine H1 receptor: Synthesis, pharmacology, and comparative molecular field analysis studies of 2-dimethylamino-5-(6)-phenyl-1,2,3,4-tetrahydronaphthalenes
Ghoneim, Ola M.,Legere, Jacqueline A.,Golbraikh, Alexander,Tropsha, Alexander,Booth, Raymond G.
, p. 6640 - 6658 (2007/10/03)
This paper reports the synthesis of a novel series of (±)-2-dimethylamino- 5- and 6-phenyl-1,2,3,4-tetrahydronaphthalene derivatives (5- and 6-APTs), and, corresponding affinity, functional activity, and, molecular modeling studies with regard to drug des
