91036-64-5Relevant academic research and scientific papers
CONFORMATIONAL BEHAVIOUR AND E/Z ISOMERIZATION OF N-ACYL AND N-AROYLHYDRAZONES
Palla, Gerardo,Predieri, Giovanni,Domiano, Paolo,Vignali, Carlo,Turner, Walter
, p. 3649 - 3654 (2007/10/02)
The stereochemical behaviour of N-acyl and N-aroylhydrazones of aromatic aldehydes, of pyruvates and of acetone, in polar and less polar solvents, has been studied by HPLC and by NMR techniques.Z/E Geometrical isomers and cis/trans amide conformers have been found for N-acylhydrazones, while for N-aroylhydrazones only geometrical isomers were detected.Energy barriers of isomers are reported, and solvent effects are discussed with regard to hydrogen bond interactions.
