91037-75-1 Usage
General Description
Glycyl-arginyl-glycyl-aspartyl-seryl-proline, also known as GRGDSP, is a peptide that plays a crucial role in cell adhesion and signaling processes. This five-amino acid sequence has been extensively studied for its ability to bind to integrins, a family of cell surface receptors that play a key role in cell adhesion to the extracellular matrix. By interacting with integrins, GRGDSP can modulate a variety of cellular functions such as cell migration, proliferation, and differentiation. Additionally, this peptide has been investigated for its potential use in tissue engineering and regenerative medicine, as it can promote the formation of new blood vessels and tissue regeneration. Overall, GRGDSP is a versatile chemical that holds promise for a wide range of biomedical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 91037-75-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,0,3 and 7 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 91037-75:
(7*9)+(6*1)+(5*0)+(4*3)+(3*7)+(2*7)+(1*5)=121
121 % 10 = 1
So 91037-75-1 is a valid CAS Registry Number.
InChI:InChI=1/C22H37N9O10/c23-8-15(33)28-11(3-1-5-26-22(24)25)18(37)27-9-16(34)29-12(7-17(35)36)19(38)30-13(10-32)20(39)31-6-2-4-14(31)21(40)41/h11-14,32H,1-10,23H2,(H,27,37)(H,28,33)(H,29,34)(H,30,38)(H,35,36)(H,40,41)(H4,24,25,26)/t11-,12-,13+,14-/m0/s1
91037-75-1Relevant articles and documents
Fibrinogen-coated particles for therapeutic use
-
, (2008/06/13)
The invention provides a particle comprising fibrinogen bound on the surface of an albumin matrix, wherein said particle is capable of coaggregation with platelet, and of aggregation in a solution containing soluble fibrinogen at a concentration of soluble fibrinogen not capable by it self of formation of a clot upon activation by thrombin.
Triurethane-protected guanidines and triflyldiurethane-protected guanidines: New reagents for guanidinylation reactions
Feichtinger, Konrad,Sings, Heather L.,Baker, Tracy J.,Matthews, Kenneth,Goodman, Murray
, p. 8432 - 8439 (2007/10/03)
New guanidinylation reagents are reported. These reagents consist of N,N',N''-tri-Boc-guanidine (1) and N,N',N''-tri-Cbz-guanidine (2), which allow for the facile conversion of alcohols to substituted guanidines. A series of arginine analogues were synthesized via condensation of a primary or secondary alcohol with the guanidinylation reagents 1 or 2, under Mitsunobu conditions, to produce protected alkylated guanidines. In addition, an extended study of the previously reported reagents N,N'-di-Boc-N''- triflylguanidine (3) and N,N'-di-Cbz-N''-triflylguanidine (4) is presented. The triflyldiurethane-protected guanidine 3 was utilized to guanidinylate primary and secondary amines under mild conditions with high yield in both solution and on solid phase.
