91047-49-3

Upstream product

• 288-32-4 1H-imidazole 
• 116-14-3 polytetrafluoroethylene 
• 20671-53-8 potassium 1H-imidazolide 
• 900534-71-6 1-(2-bromo-1,1,2,2-tetrafluoroethyl)-1H-imidazole 
• 555-16-8 4-nitrobenzaldehdye 
• 113939-45-0 1-bromo-4-(2-bromo-1,1,2,2-tetrafluoroethoxy)benzene 

Downstream Products

• 1423009-78-2 1-methyl-3-(α,α,β,β-tetrafluoroethyl)imidazolium 2,4,6-tris(fluorosulfonyl)phenolate 

Relevant academic research and scientific papers

Nucleophilic tetrafluoroethylation employing in situ formed organomagnesium reagents

Tetrafluoroalkyl bromides are metalated with equimolar iPrMgCl·LiCl (Turbo Grignard) to form organomagnesium compounds which are stable at low temperatures and react with various electrophiles (aldehydes, ketones, CO2, cyclic sulfate and sulfamidate, N-sulfonylimines, nitrone, chlorophosphate, nonaflyl azide) to afford novel functionalized tetrafluoroethylene-containing products. Ease of operation, excellent selectivity, high nucleophilicity, and enhanced stability of the reactive species together with a broad substrate scope comprise a highly attractive nucleophilic tetrafluoroethylation protocol affording unique synthetic building blocks.

Antibacterial Activity of Imidazolium-Based Ionic Liquids Investigated by QSAR Modeling and Experimental Studies

Predictive QSAR models for the inhibitors of B. subtilis and Ps. aeruginosa among imidazolium-based ionic liquids were developed using literary data. The regression QSAR models were created through Artificial Neural Network and k-nearest neighbor procedures. The classification QSAR models were constructed using WEKA-RF (random forest) method. The predictive ability of the models was tested by fivefold cross-validation; giving q2 = 0.77–0.92 for regression models and accuracy 83–88% for classification models. Twenty synthesized samples of 1,3-dialkylimidazolium ionic liquids with predictive value of activity level of antimicrobial potential were evaluated. For all asymmetric 1,3-dialkylimidazolium ionic liquids, only compounds containing at least one radical with alkyl chain length of 12 carbon atoms showed high antibacterial activity. However, the activity of symmetric 1,3-dialkylimidazolium salts was found to have opposite relationship with the length of aliphatic radical being maximum for compounds based on 1,3-dioctylimidazolium cation. The obtained experimental results suggested that the application of classification QSAR models is more accurate for the prediction of activity of new imidazolium-based ILs as potential antibacterials.

A mild hydrodehalogenation of fluoroalkyl halides

A mild hydrodehalogenation reaction of fluoroalkyl halides (RfCF2X, X = Br, I) has been developed under weakly basic conditions, giving the corresponding hydrogenolysis products with moderate to high yields.

PROCESSES FOR MAKING DIALKYL ETHERS FROM ALCOHOLS

Processes for the preparation of dialkyl ethers from C4 to C8 straight-chain alcohols using an ionic liquid.

PROCESSES FOR MAKING DIBUTYL ETHERS FROM ISOBUTANOL

Processes for preparing dibutyl ethers from isobutanol using an ionic liquid.

PROCESSES FOR MAKING DIBUTYL ETHERS FROM 2-BUTANOL

Processes for preparing dibutyl ethers from 2-butanol using an ionic liquid.

METHOD FOR PRODUCTION OF HETEROAROMATIC RING COMPOUND HAVING N-Rf GROUP

There is provided a preparation process in which a N-H group of a heteroaromatic ring compound having a N-H group in its ring is converted directly to a N-Rf group at a high reaction efficiency without using a catalyst. The preparation process is a process for preparing a compound comprising a heteroaromatic ring structure having a N-Rf group (-Rf is a fluorine-containing organic group) in its ring and is characterized in that the heteroaromatic ring compound having a N-H group in its ring is allowed to react with fluoroalkene in the absence of an alkali metal.

Ionic liquids

Compositions of matter useful as ionic liquids of the formula Z+A?, wherein Z+ is a cation selected from the group consisting of pyridinium, pyridazinium, pyrimidinium, pyrazinium, imidazolium, pyrazolium, thiazolium, oxazolium, triazolium, and phosphonium, ammonium cations with specified substituents, and A? is selected from the group consisting of the following three anions wherein R11, R12 and R13 are as specified. R11—CHF—CF2—SO3???Formula I R12—CF2—CF2—SO3???Formula II (R13—CHF—CF2—SO2)2N???Formula III

UTILIZING IONIC LIQUIDS FOR HYDROFLUOROCARBON SEPARATION

The present invention relates to a process for separating close-boiling and azeotropic components of mixtures, wherein said mixtures comprise at least one hydrofluorocarbon compound, using at least one ionic liquid.

Olefin isomerization

This invention relates to a process for isomerizing olefins; the reaction is carried out in the presence of at least one ionic liquid.