910471-00-0

Upstream product

• 90857-62-8 ((E)-1,3-Dimethoxy-buta-1,3-dienyloxy)-trimethyl-silane 
• 878193-80-7 (E)-2-(benzylideneamino)-4-methylphenol 

Downstream Products

• 910471-15-7 Toluene-4-sulfonic acid (R)-1-(2-hydroxy-5-methyl-phenyl)-6-oxo-2-phenyl-1,2,3,6-tetrahydro-pyridin-4-yl ester 
• 916592-54-6 4-hydroxy-1-(2-hydroxy-5-methyl-phenyl)-6-phenyl-5,6-dihydro-1H-pyridin-2-one 

Relevant academic research and scientific papers

Chiral Bronsted acid catalyzed enantioselective aza-Diels-Alder reaction of Brassard's diene with imines

(Chemical Equation Presented) Bronsted, Brassard, Diels, and Alder: Aldimines 1 undergo aza-Diels-Alder reactions with Brassard's diene 2 in the presence of a chiral cyclic phosphate pyridinium salt 4 as a chiral Bronsted acid to give α,β-unsaturated δ-la

Enantioselective aza-Diels-Alder reaction of Brassard's diene with aldimines catalyzed by chiral N,N′-dioxide-Yb(OTf)3 complex

The chiral N,N′-dioxide-Yb(OTf)3 complex-catalyzed enantioselective aza-Diels-Alder reaction of Brassard's diene with aldimines has been developed, giving the corresponding α,β-unsaturated δ-lactam derivatives in moderate yields with good enantioselectivities (up to 81% ee and up to 99% ee by single recrystallization) under mild conditions. Isolation of the reaction intermediate indicates that this asymmetric aza-Diels-Alder reaction proceeds through a stepwise Mannich-type pathway.