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3-(4-tert-butylphenyl)-N-[4-(methylsulfonamido)-3-nitrobenzyl]propanamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

910534-72-4

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910534-72-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 910534-72-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,0,5,3 and 4 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 910534-72:
(8*9)+(7*1)+(6*0)+(5*5)+(4*3)+(3*4)+(2*7)+(1*2)=144
144 % 10 = 4
So 910534-72-4 is a valid CAS Registry Number.

910534-72-4Downstream Products

910534-72-4Relevant academic research and scientific papers

Synthesis and structural optimization of multiple H-bonding region of diarylalkyl (thio)amides as novel TRPV1 antagonists

Li, Fu-Nan,Kim, Nam-Jung,Chang, Dong-Jo,Jang, Jaebong,Jang, Hannah,Jung, Jong-Wha,Min, Kyung-Hoon,Jeong, Yeon-Su,Kim, Sun-Young,Park, Young-Ho,Kim, Hee-Doo,Park, Hyeung-Geun,Suh, Young-Ger

experimental part, p. 8149 - 8160 (2010/03/25)

Structural optimization of multiple H-bonding region and structure-activity relationship of diarylalkyl amides/thioamides as novel TRPV1 antagonists are described. In particular, we identified amide 34o and thioamides 35o and 35r, of which antagonistic activities were highly enhanced by an incorporation of cyano or vinyl-substituent to the multiple H-bonding region. They exhibited potent 45Ca2+ uptake inhibitions in rat DRG neuron with IC50s of 25, 32 and 28 nM, respectively.

NOVEL COMPOUNDS, ISOMER THEREOF OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

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Page/Page column 52-53, (2010/11/23)

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1 )antagonist; and a pharmaceutical composition containing the same. The present invention

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