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(E)-3-(4-tert-butylphenyl)-N-(3-fluoro-4-(methylsulfonamido)benzyl)acrylamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

910534-75-7

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910534-75-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 910534-75-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,0,5,3 and 4 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 910534-75:
(8*9)+(7*1)+(6*0)+(5*5)+(4*3)+(3*4)+(2*7)+(1*5)=147
147 % 10 = 7
So 910534-75-7 is a valid CAS Registry Number.

910534-75-7Downstream Products

910534-75-7Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of novel diarylalkyl amides as TRPV1 antagonists

Li, Fu-Nan,Kim, Nam-Jung,Paek, Seung-Mann,Kwon, Do-Yeon,Min, Kyung Hoon,Jeong, Yeon-Su,Kim, Sun-Young,Park, Young-Ho,Kim, Hee-Doo,Park, Hyeung-Geun,Suh, Young-Ger

experimental part, p. 3557 - 3567 (2009/09/27)

We have developed a new class of diarylalkyl amides as novel TRPV1 antagonists. They exhibited potent 45Ca2+ uptake inhibitions in rat DRG neuron. In particular, the amide 59 was identified as a potent antagonist with IC50 of 57 nM. The synthesis and structure-activity relationship of the diarylalkyl amides are also described.

NOVEL COMPOUNDS, ISOMER THEREOF OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

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Page/Page column 58, (2010/11/23)

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1 )antagonist; and a pharmaceutical composition containing the same. The present invention

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