910536-25-3Relevant academic research and scientific papers
Identification of novel, selective and potent Chk2 inhibitors
Larson, Gary,Yan, Shunqi,Chen, Huanming,Rong, Frank,Hong, Zhi,Wu, Jim Zhen
, p. 172 - 175 (2007/10/03)
A series of isothiazole carboxamidine compounds were synthesized and discovered as novel and selective inhibitors for Chk2. They are not active against the related Chk1 kinase. The structure-activity relationship studies were performed on the scaffold, an
