910537-24-5 Usage
Uses
Used in Research Applications:
HT-2 Toxin-13C2,D3 is used as a research tool for studying the effects of trichothecene mycotoxins on DNA damage and cell death. Its labeled nature allows for easier detection and tracking in experimental settings, providing valuable insights into the mechanisms of action and potential applications in various fields.
Used in Pharmaceutical Development:
HT-2 Toxin-13C2,D3 can be utilized in the development of pharmaceuticals targeting specific cellular pathways or mechanisms related to DNA damage and cell death. Its unique properties may contribute to the discovery of novel therapeutic agents or the improvement of existing treatments.
Used in Environmental Monitoring:
HT-2 Toxin-13C2,D3 can be employed in environmental monitoring programs to detect and quantify the presence of trichothecene mycotoxins in various samples, such as food, water, or air. This can help in assessing the risk of exposure to these harmful substances and implementing appropriate safety measures.
Used in Agricultural Applications:
HT-2 Toxin-13C2,D3 can be used in agricultural research to study the impact of trichothecene mycotoxins on crop health and productivity. Understanding the effects of these toxins on plants can lead to the development of more resistant crop varieties or effective strategies to mitigate their harmful effects.
Check Digit Verification of cas no
The CAS Registry Mumber 910537-24-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,0,5,3 and 7 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 910537-24:
(8*9)+(7*1)+(6*0)+(5*5)+(4*3)+(3*7)+(2*2)+(1*4)=145
145 % 10 = 5
So 910537-24-5 is a valid CAS Registry Number.
910537-24-5Relevant articles and documents
Synthesis of four carbon-13-labeled type A trichothecene mycotoxins and their application as internal standards in stable isotope dilution assays
Asam, Stefan,Rychlik, Michael
, p. 6535 - 6546 (2008/09/21)
The first stable isotope dilution assay (SIDA) for the simultaneous quantitation of the most abundant type A trichothecenes in foods and feeds was developed. Synthesis of carbon-13-labeled T2-toxin, HT2-toxin, diacetoxyscirpenol, and monoacetoxyscirpenol was accomplished by [ 13C2]-acetylation of T2-triol and scirpentriol, respectively. Scirpentriol was prepared from diacetoxyscirpenol by complete alkaline hydrolysis and subsequently was converted to [13C 6]-triacetoxyscirpentriol by peracetylation with [13C 4]-acetic anhydride. The latter compound was selectively hydrolyzed using ammonium hydroxide to give [13C4]-diacetoxyscirpenol and [13C2]-monoacetoxyscirpenol in reasonable yields. Analogously, [13C6]-T2-triacetate was prepared from T2-triol and subjected to controlled hydrolysis to yield [13C 4]-T2-toxin and [13C2]-HT2-toxin. All synthesized products were characterized by NMR and MS experiments. Using the prepared isotopically labeled standards, SIDAs were developed for the quantitation of type A trichothecenes in food and feeds. The mycotoxins were quantified by LC-single and tandem MS after cleanup on multifunctional columns. The method revealed good sensitivity with low detection and quantification limits along with excellent recovery and good precision in interassay studies. Food samples were analyzed using the developed SIDA and showed substantial contamination of oat products with T2-toxin and HT2-toxin. Diacetoxyscirpenol was detected on potatoes, whereas monoacetoxyscirpenol was not present in the analyzed samples.
