910540-73-7Relevant academic research and scientific papers
Improved synthetic method of Benzo[a]pheno-selenazinium phototherapeutic agents
Yue, Xiuxiu,Xu, Jing,Liu, Xiaozhong,Song, Xiangzhi,Foley, James W.
, (2021)
Benzo[a]phenoselenazinium dyes are excellent photodynamic therapeutic agents that have a red absorption (660 nm), high singlet oxygen quantum yield (>0.8), and good water-solubility and liposolubility. Bis-(3-diethylaminophenyl) diselenide, the most impor
Synthesis and properties of benzo[a]phenoxazinium chalcogen analogues as novel broad-spectrum antimicrobial photosensitizers
Foley, James W.,Song, Xiangzhi,Demidova, Tatiana N.,Jilal, Fatima,Hamblin, Michael R.
, p. 5291 - 5299 (2006)
The goal of this investigation was to develop improved photosensitizers for use as antimicrobial drugs in photodynamic therapy of localized infections. Replacement of the oxygen atom in 5-(ethylamino)-9-diethylaminobenzo[a] phenoxazinium chloride (1) with
Conditionally Activatable Photoredox Catalysis in Living Systems
Gebremedhin, Kalayou Hiluf,Kim, Jong Seung,Li, Mingle,Ma, Dandan,Peng, Xiaojun,Pu, Zhongji,Xiong, Tao,Xu, Yunjie
, p. 163 - 173 (2022/01/08)
The transformational effect of photoredox catalytic chemistries has inspired new opportunities, enabling us to interrogate nature in ways that are not possible otherwise and to unveil new biotechnologies in therapy and diagnosis. However, the deployment o
PHOTOSENSITIZER AND DERIVATIVES AND APPLICATION THEREOF
-
, (2021/02/05)
A photosensitizer and derivative, application thereof. The photosensitizer has the structure of general formula I, wherein X is S or Se, Y is organic or inorganic ion, R1 and R2 are independently selected from H, alkyl, alkoxy, alkyl
Benzo[a]phenoselenazine-based NIR photosensitizer for tumor-targeting photodynamic therapy via lysosomal-disruption pathway
Gebremedhin, Kalayou H.,Li, Mingle,Gao, Fengli,Gurram, Bhaskar,Fan, Jiangli,Wang, Jingyun,Li, Yaming,Peng, Xiaojun
, (2019/06/19)
The ultimate goal of cancer therapy is to develop antitumor agents that will destroy selectively tumor cells while sparing the health cell of the patient. Herein, we reported a novel tumor-specific and lysosome dual-targeted NIR photosensitizer, Se-Biotin
A specific photosensitizer compound for a target cell.
-
Paragraph 0043; 0047; 0049, (2017/08/23)
PROBLEM TO BE SOLVED: To provide a photosensitization compound which can apply oxidation stress selectively to a target cell, particularly a reporter enzyme expression cell such as β-galactosidase.SOLUTION: A selective photosensitization compound includes a compound represented by general formula (I) or salt thereof, where A represents a univalent group cut by an enzyme; R, R, R, R, R, and Rrepresent a hydrogen atom, a hydroxyl group or the like; and X represents a C-Calkylene group.
Antimicrobial photoinactivation using chalcogen analogs of benzo(A)phenoxazinium dyes
-
Page/Page column 14-15, (2010/11/29)
Compositions and methods for the use of photoactivatable antimicrobial chalcogen analogs of benzophenoxazinium dyes in the treatment of infections are provided.
