910547-60-3Relevant academic research and scientific papers
Linear dicationic terphenyls and their aza analogues as antiparasitic agents
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Page/Page column 33, (2010/11/25)
Novel dicationic terphenyl compounds and their aza analogues. Methods for combating microbial infections with novel dicationic terphenyl compounds and their aza analogues. Processes for synthesizing novel dicationic terphenyl compounds and their aza analo
Synthesis, DNA affinity, and antiprotozoal activity of linear dications: Terphenyl diamidines and analogues
Ismail, Mohamed A.,Arafa, Reem K.,Brun, Reto,Wenzler, Tanja,Miao, Yi,Wilson, W. David,Generaux, Claudia,Bridges, Arlene,Hall, James E.,Boykin, David W.
, p. 5324 - 5332 (2007/10/03)
Diamidines 10a-g and 18a,b were obtained from dinitriles 9a-g and 15a,b by treatment with lithium trimethylsilylamide or upon hydrogenation of bis-O-acetoxyamidoximes. Dinitriles 9a-g were prepared via Suzuki reactions between arylboronic acids and arylni
DICATIONIC TRIARYL ANALOGS AS ANTI-PROTOZOAN AGENTS
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Page/Page column 76, (2008/06/13)
Novel dicationic, heterocyclic triaryl compounds are useful in the treatment of microbial infections, such as Trypanosoma brucei rhodesiense infection and Plasmodium falciparum infection. These compounds are accordingly useful in treating second-stage human African trypanosomiasis. Pharmaceutical formulations comprising these compounds can be used in methods of treating microbial infections.
