910568-52-4

Upstream product

• 316810-08-9 2-ethoxy-4-cyanobenzoic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 

Relevant academic research and scientific papers

4,4,5,5, Tetrasubstituted imidazolines

There is provided a compound of formula I and the pharmaceutically acceptable salts and esters thereof wherein X1, X2, R1, R2, R3, R4, R5 and R6 are herein described. The compounds exhibit activity as anticancer agents.

Cis-imidazolines

There are presented compounds of the formula or pharmaceutically acceptable salts thereof, wherein Y1, Y2, X1, X2, X3 and R are as described in this application. These compounds are believed to inhibit MDM2-p53 interaction and as such the compounds will have anti-hyperproliferative cellular activity.