91064-25-4

Usage

Uses

Used in Pharmaceutical Industry:
1-(3,4-DICHLOROPHENYL)-5-OXO-3-PYRROLIDINECARBOXYLIC ACID serves as a crucial intermediate in the development of pharmaceuticals. Its specific structure allows it to be a building block in the synthesis of various medicinal compounds, potentially contributing to the creation of new drugs with different therapeutic applications.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, 1-(3,4-DICHLOROPHENYL)-5-OXO-3-PYRROLIDINECARBOXYLIC ACID acts as an intermediate for synthesizing a range of products. It may be utilized in the production of pesticides, herbicides, or other chemical agents that are designed to protect crops and enhance agricultural productivity.
Given the compound's role as an intermediate, its applications are primarily in the synthesis and production processes of various industries. Further exploration into its chemical properties and reactivity could potentially reveal additional uses, expanding its relevance in both existing and emerging fields.

Upstream product

• 97-65-4 2-methylenesuccinic acid 
• 95-76-1 m,p-dichloroaniline 

Downstream Products

• 133748-09-1 methyl 1-(3,4-dichlorophenyl)-5-oxo-3-pyrrolidinecarboxylate 
• 133748-11-5 Methyl 4-[1-(3,4-dichlorophenyl)-2-pyrrolidon-4-yl]methoxybenzoate 
• 1027552-96-0 Methanesulfonic acid 1-(3,4-dichloro-phenyl)-5-oxo-pyrrolidin-3-ylmethyl ester 
• 133748-10-4 1-(3,4-Dichlorophenyl)-4-hydroxymethyl-2-pyrrolidone 
• 848317-73-7 N-(3,4-dichlorophenyl)-3-formylpyrrole 
• 848317-69-1 [N-(3,4-dichlorophenyl)pyrrolidin-3-yl]methanol 
• 1207473-54-8 1-(3,4-dichloro-phenyl)-5-chloro-pyrrole-2,4-dicarbaldehyde 

Relevant academic research and scientific papers

The discovery of new plant activators and scaffolds with potential induced systemic resistance: From jasmonic acid to pyrrolidone

Plants can develop multifaceted system resistance as a result of infection with pathogens, insects, and some specific microbes or after treatment with specific chemicals.1 Among them, systemic acquired resistance (SAR) and induced systemic resi

N-Aryl pyrrolidinonyl oxadiazoles as potent mGluR5 positive allosteric modulators

A novel series of N-aryl pyrrolidinonyl oxadiazoles were identified as mGluR5 positive allosteric modulators (PAMs). Optimization of the initial lead compound 6a led to the identification of the 12c (-) enantiomer as a potent compound with acceptable in vitro clearance, CYP, hERG and PK properties. Para substituted N-aryl pyrrolidinonyl oxadiazoles are mGluR5 PAMs while the meta and ortho substituted N-aryl pyrrolidinonyl oxadiazoles are negative allosteric modulators (NAMs). Para fluoro substitution on the N-aryl group and meta chloro or methyl substituents on the aryl oxadiazole moiety are optimal for mGluR5 PAM efficacy. The existence of an exquisitely sensitive 'PAM to NAM switch' within this chemotype making it challenging for simultaneous optimization of potency and drug-like properties.

Sodium borohydride-iodine mediated reduction of γ-lactam carboxylic acids followed by DDQ mediated oxidative aromatisation: a simple approach towards N-aryl-formylpyrroles and 1,3-diaryl-formylpyrroles

A simple methodology for the conversion of substituted N-aryl-γ-lactam 2/3-carboxylic acids to substituted N-aryl-2/3-formyl-pyrroles has been developed. Several N-aryl-γ-lactam 2/3-carboxylic acids were reduced to substituted (N-aryl-pyrroliden-2/3-yl)-m

Synthesis of 4-methyloxybenzoic acids and related compounds, and their inhibitory capacities toward fatty-acid and sterol biosynthesis

The synthesis of a series of 4-methyloxybenzoic acids and related compounds, and their evaluation for inhibitory capacity toward fatty-acid and sterol biosyntheses using rats' liver slices in vitro and rabbits