910647-38-0Relevant academic research and scientific papers
Total synthesis of fuzinoside
He, Ping,Li, Xiao-Huan,Chen, Qiao-Hong,Yang, Jing-Song,Wang, Feng-Peng
, p. 4022 - 4030 (2014/06/09)
The first total syntheses of fuzinoside (1b) were achieved from d-galactose through two strategies (BCA and ABC) in 11 (total yield: 5.0%) and 15 (total yield: 3.7%) steps, respectively. Comparison of NMR data of synthetic compound 1b and those of the fuzinoside isolated from the lateral roots of Aconitum carmicaelii suggests that the structure reported in the literature1,2 might not be accurate. The synthetic fuzinoside (1b) exhibited moderate cardiac activity in the isolated bullfrog heart assay.
Facile synthesis of per-O-tort-butyldimethylsilyl-β-D-galactofuranose and efficient glyeosylation via the galactofuranosyl iodide
Baldoni, Luciana,Marino, Carla
supporting information; experimental part, p. 1994 - 2003 (2009/08/07)
The synthesis of crystalline per-0-TBS-β-D-galactofuranose (Aβ) as a new precursor of D-Galf units is described. Anomeric iodination by reaction with TMSI followed by in situ coupling with simple alcohols and a wide variety of glycosyl acceptors, in the absence of a promoter, was employed as a new efficient glycosylation method for the assembly of D-galactofuranosyl moieties with high β-stereoselectivity. Under the mild conditions of this reaction labile protective groups, like acetals, and furanosyl linkages are preserved.
Facile synthesis of benzyl β-d-galactofuranoside. A convenient intermediate for the synthesis of d-galactofuranose-containing molecules
Marino, Karina,Baldoni, Luciana,Marino, Carla
, p. 2286 - 2289 (2007/10/03)
Benzyl β-d-galactofuranoside was efficiently obtained from 1,2,3,5,6-penta-O-benzoyl-α,β-d-galactofuranose, via benzyl 2,3,5,6-tetra-O-benzoyl-β-d-galactofuranoside. Conditions for the O-debenzylation were investigated in order to evaluate the synthetic a
