910648-94-1

Upstream product

• 910649-49-9 6-bromo-3-pyridinyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside 
• 1765-93-1 4-fluoroboronic acid 

Relevant academic research and scientific papers

Palladium-catalyzed C-C coupling: efficient preparation of new 5-thio-β-d-xylopyranosides as oral venous antithrombotic drugs

First examples of a Suzuki and Stille cross-coupling reaction to prepare derivatives of pyridinyl 5-thio-β-d-xylopyranosides are described. Some of these compounds are orally active in an animal model of venous thrombosis.

Novel Compounds Derived From 5-Thioxylose And Their Use In Therapeutics

The invention relates to novel 5-thioxylose compounds, preferably derivatives of the 5-thioxylopyranose type, to the process for their preparation and to their use as active principles of drugs intended especially for the treatment or prevention of thrombosis or cardiac insufficiency.