91066-65-8 Usage
Properties
Purine core
Chlorine atom at the 6th position
Cyclohexenyl group at the 9th position
Classification
Purine derivative
Uses
Medicinal chemistry, drug development
Pharmacological activities
Antiviral, anticancer, anti-inflammatory
Importance
Valuable building block for synthesis of biologically active molecules
Application
Starting material for creation of new pharmaceutical compounds
Research focus
Important target for research and development in medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 91066-65-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,0,6 and 6 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 91066-65:
(7*9)+(6*1)+(5*0)+(4*6)+(3*6)+(2*6)+(1*5)=128
128 % 10 = 8
So 91066-65-8 is a valid CAS Registry Number.
91066-65-8Relevant academic research and scientific papers
First synthesis of (-)-neplanocin C
Comin, María J.,Rodriguez, Juan B.
, p. 4639 - 4649 (2007/10/03)
(-)-Neplanocin C (4), a minor component of the neplanocin family of antibiotics and a lead drug for the design of several conformationally constrained nucleosides analogues, was enantioselectively synthesized starting from D-ribono-1,4-lactone via a convergent approach in twelve steps. The proton NMR spectrum of 4 was in agreement with the corresponding natural product. Calculated coupling constants obtained from ab initio molecular modeling studies and from previously published X-ray structure of neplanocin C also corresponded to the spectroscopic data. (C) 2000 Elsevier Science Ltd.