910817-43-5

Basic information

• Product Name: (3R,4R)-4-amino-1-((4-(4-fluoro-3-methoxyphenylamino) quinazolin-5-yl)methyl)piperidin-3-ol
• Synonyms: (3R,4R)-4-amino-1-((4-(4-fluoro-3-methoxyphenylamino) quinazolin-5-yl)methyl)piperidin-3-ol
• CAS NO: 910817-43-5
• Molecular Weight: 397.452
• Mol File: 910817-43-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,4R)-4-amino-1-((4-(4-fluoro-3-methoxyphenylamino) quinazolin-5-yl)methyl)piperidin-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R)-4-amino-1-((4-(4-fluoro-3-methoxyphenylamino) quinazolin-5-yl)methyl)piperidin-3-ol(910817-43-5)
• EPA Substance Registry System: (3R,4R)-4-amino-1-((4-(4-fluoro-3-methoxyphenylamino) quinazolin-5-yl)methyl)piperidin-3-ol(910817-43-5)

Safety Data

• Hazardous Substances Data: 910817-43-5(Hazardous Substances Data)

Upstream product

• 910817-92-4 (3R,4R)-4-azido-1-((4-(methylthio)quinazolin-5-yl)methyl)piperidin-3-ol 
• 64465-53-8 4-fluoro-3-methoxyaniline 

Relevant articles and documents

ATP competitive kinase inhibitors

The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.