910896-11-6Relevant academic research and scientific papers
Revisiting the Influence of Silver in Cationic Gold Catalysis: A Practical Guide
Lu, Zhichao,Han, Junbin,Hammond, Gerald B.,Xu, Bo
, p. 4534 - 4537 (2015)
An excess amount of silver salt to generate cationic gold from a gold catalyst precursor such as L-Au-Cl almost always has adverse effects on the reactivity of the cationic gold catalyst. A preformed L-Au+X- complex, generated by sonication followed by centrifugation, increases the reactivity in a gold catalyzed reaction. The adverse silver effect might be caused by the interaction of silver salts with gold intermediates.
An efficient and selective synthesis of 2,5-substituted pyrroles by gold-catalysed ring expansion of alkynyl aziridines
Davies, Paul W.,Martin, Nicolas
scheme or table, p. 159 - 164 (2011/02/16)
A range of substituted alkynyl aziridines undergo a ring expansion to afford 2,5-substituted pyrroles under gold catalysis. While effective conditions can be generated from other gold sources, a combination of Ph3PAuCl and AgOTs generate a cata
Counterion effects in a gold-catalyzed synthesis of pyrroles from alkynyl aziridines
Davies, Paul W.,Martin, Nicolas
supporting information; experimental part, p. 2293 - 2296 (2009/10/02)
Aryl-substituted N-tosyl alkynyl aziridines undergo a gold-catalyzed ring expansion to afford 2,5-substituted pyrrole products. Under certain conditions, a ring-expansion and rearrangement leads to 2,4-substituted pyrroles. The reaction pathway is determi
A facile and regioselective synthesis of 2,5-disubstituted pyrroles via gold-catalyzed cycloisomerization of acetylenylaziridines
Chen, Dong-Dong,Hou, Xue-Long,Dai, Li-Xin
supporting information; experimental part, p. 6944 - 6946 (2010/02/27)
Gold-catalyzed cycloisomerization reaction of acetylenylaziridines provides 2,5-disubstituted pyrroles in high yields. The presence of protic species accelerates the reaction rate and improves the yields of pyrrole products.
METHODS FOR THE SYNTHESIS OF HETEROAROMATIC COMPOUNDS
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Page/Page column 36, (2008/06/13)
Methods of making heteroaromatic compounds comprising a 5- membered ring, and dihydro forms thereof, by a metal catalysed 5-endo-cyclisation of alkynes (acetylenes) are disclosed. The methods involve the use of a catalyst comprising a silver salt, more preferably a silver (I) salt, which is employed as a heterogeneous catalyst for the cyclisation reaction. The methods can produce different types of heteroaromatic compounds and are capable of producing highly substituted products, i.e. products in which the 5-membered ring is disubstituted, trisubstituted or, with further simple reactions, tetrasubstituted. The methods described herein generally the advantages that they use conditions and reagents that are benign, cheap and flexible and amenable to scale up, and in which the only by-product is water.
