910904-67-5 Usage
General Description
2,5-Pyrimidinediamine, N2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-, also known as PD153035, is a chemical compound that belongs to the class of pyrimidines. It is a potent and selective inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR), which plays a crucial role in the regulation of cell growth, proliferation, and survival. PD153035 has been extensively studied for its potential therapeutic applications in cancer treatment, particularly in targeting EGFR-dependent tumors. Its ability to inhibit EGFR activity makes it a promising candidate for the development of novel anti-cancer drugs and has been the focus of numerous research studies for its potential role in treating various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 910904-67-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,0,9,0 and 4 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 910904-67:
(8*9)+(7*1)+(6*0)+(5*9)+(4*0)+(3*4)+(2*6)+(1*7)=155
155 % 10 = 5
So 910904-67-5 is a valid CAS Registry Number.
910904-67-5Relevant articles and documents
2-AMINO-5-SUBSTITUTED PYRIMIDINE INHIBITORS
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, (2010/11/29)
Compounds having the general structure (A) are provided. The compounds of the invention are capable of inhibiting kinases, such as members of the Src kinase family, Vegfr and various other specific receptor and non-receptor kinases. Formula (I):
