91092-41-0Relevant academic research and scientific papers
Synthesis of Enantioenriched α,α-Dichloro- and α,α-Difluoro-β-Hydroxy Esters and Amides by Ruthenium-Catalyzed Asymmetric Transfer Hydrogenation
Zheng, Long-Sheng,Phansavath, Phannarath,Ratovelomanana-Vidal, Virginie
supporting information, p. 5107 - 5111 (2018/09/13)
A mild and convenient approach was developed to prepare a series of α,α-dihalogeno β-hydroxy esters or amides by using commercially available Noyori's complex [RuCl(p-cymene)(R,R)-TsDPEN] as a catalyst (S/C = 100?200) in the asymmetric transfer hydrogenat
Hydrogen peroxide or peracetic acid mediated self-titrating α-halogenation of 1,3-dicarbonyl compounds
Akula, Ramulu,Galligan, Marc J.,Ibrahim, Hasim
experimental part, p. 347 - 351 (2011/03/18)
Efficient oxidative -halogenation of 1,3-dicarbonyl compounds has been achieved by employing a system comprising of sub-stoichiometric amounts of TiX4 (X = Cl, Br) in conjunction with environmentally benign hydrogen peroxide (H2Osub
Umpolung of halide reactivity: Efficient (diacetoxyiodo)benzene-mediated electrophilic α-halogenation of 1,3-dicarbonyl compounds
Akula, Ramulu,Galligan, Marc,Ibrahim, Hasim
experimental part, p. 6991 - 6993 (2010/04/25)
An efficient high-yielding (diacetoxyiodo)benzene-mediated α-halogenation of 1,3-dicarbonyl compounds utilising titanium tetrahalides as the halide source has been developed. The Royal Society of Chemistry 2009.
Highly stereoselective synthesis of anti-N-protected-α-amino epoxides
Hoffman,Weiner,Maslouh
, p. 5790 - 5795 (2007/10/03)
A simple and efficient method for the synthesis of anti-N-protected amino epoxides from carbamate-protected amino acids is described. The two key steps are the monobromination of a β-ketoester and chelation-controlled reduction of a bromomethyl ketone intermediate. Good overall yields, high diastereoselectivity, and excellent functional group compatibility are characteristic.
