911-76-2

Basic information

• Product Name: ()-N-[4-[(aminoiminomethyl)amino]-1-[[(4-nitrophenyl)amino]carbonyl]butyl]benzamide
• Synonyms: Benzoylarginine nitroanilide; (1)-N-(4-((Aminoiminomethyl)amino)-1-(((4-nitrophenyl)amino)carbonyl)butyl)benzamide; Benzamide, N-(4-((aminoiminomethyl)amino)-1-(((4-nitrophenyl)amino)carbonyl)butyl)-, (+-)-; N-{5-[(diaminomethylidene)amino]-1-[(4-nitrophenyl)amino]-1-oxopentan-2-yl}benzamide; N-{1-(benzoylamino)-4-[(diaminomethylidene)amino]butyl}-4-nitrobenzamide hydrochloride (1:1)
• CAS NO: 911-76-2
• Molecular Formula: C₁₉H₂₂N₆O₄
• Molecular Weight: 434.8767
• EINECS: 213-010-7
• Mol File: 911-76-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ()-N-[4-[(aminoiminomethyl)amino]-1-[[(4-nitrophenyl)amino]carbonyl]butyl]benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: ()-N-[4-[(aminoiminomethyl)amino]-1-[[(4-nitrophenyl)amino]carbonyl]butyl]benzamide(911-76-2)
• EPA Substance Registry System: ()-N-[4-[(aminoiminomethyl)amino]-1-[[(4-nitrophenyl)amino]carbonyl]butyl]benzamide(911-76-2)

Safety Data

• Hazardous Substances Data: 911-76-2(Hazardous Substances Data)

Usage

General Description

The chemical compound "()-N-[4-[(aminoiminomethyl)amino]-1-[[(4-nitrophenyl)amino]carbonyl]butyl]benzamide" is a benzamide derivative with a complex molecular structure. It contains a benzene ring with a butyl chain and a carbonyl group attached to it. Additionally, it has a nitrophenyl group and an aminoiminomethylamino group incorporated into its structure. ()-N-[4-[(aminoiminomethyl)amino]-1-[[(4-nitrophenyl)amino]carbonyl]butyl]benzamide has potential applications in the field of pharmaceuticals, as it may exhibit biological activity due to its structural features. Furthermore, further research and study are required to understand its potential uses and properties in various applications.

Upstream product

• 154-92-7 Nα-benzoyl-L-arginine 
• 100-01-6 4-nitro-aniline 

Downstream Products

• 100-01-6 4-nitro-aniline 
• 154-92-7 Nα-benzoyl-L-arginine 
• 7759-68-4 N-benzoyl-dl-arginine 
• 6453-58-3 N-α-benzoyl-DL-arginine 

Relevant articles and documents

Acid-Sensitive Latent Inhibitors for Proteolytic Enzymes: Synthesis and Characterization

The reaction between peptide aldehydes and acylhydrazones affords derivatives that represent potential prodrugs for selective inhibition of lysosomal enzymes.BzPheal=Ala, obtained from the reaction between N-benzoyl-L-phenylalaninal and N-acetyl-L-alanine hydrazide, has been most carefully studied.When BzPheal=Ala is introduced into ongoing reactions catalyzed by α-chymotrypsin or papain, the rate of these reactions diminishes more rapidly with time than do those of controls lacking BzPheal=Ala.Furthermore, the disparity between run and control is much greater at pH 5 than at pH 7.The extent of inhibition (defined as explained in the text) at pH 5 can exceed that at pH 7 by 25-40-fold.The data are quantitatively explained by a reaction scheme that recognizes three important properties of BzPheal=Ala: (1) It undergoes hydrolysis at pH 5-7 to regenerate N-benzoyl-L-phenylalaninal; (2) the aldehyde thus liberated is a far more potent inhibitor for serine or cysteine proteases than is BzPheal=Ala; and (3) the rate constant for hydrolysis of BzPheal=Ala at pH 5 greatly exceeds that at pH 7.