911099-44-0Relevant academic research and scientific papers
A Maillard approach to 2-formylpyrroles: Synthesis of magnolamide, lobechine and funebral
Yuen, Tsz-Ying,Eaton, Samantha E.,Woods, Tom M.,Furkert, Daniel P.,Choi, Ka Wai,Brimble, Margaret A.
, p. 1431 - 1437 (2014)
A convenient synthesis of the traditional medicine constituents magnolamide, lobechine and funebral is described. Construction of the 2-formylpyrrole core of these natural products was achieved by means of a Maillard reaction, involving condensation of the sugar surrogate, dihydropyranone 9, with the requisite primary amines. This approach offers a very direct and general route to the 2-formylpyrrole ring system. The synthesis of the 2-formylpyrrole core found in the traditional medicine constituents, magnolamide, lobechine and funebral, was constructed by a Maillard reaction, involving condensation of the sugar surrogate, dihydropyranone 9, with the requisite primary amines. This approach offers a very direct and general route to the 2-formylpyrrole ring system. Copyright
A Maillard Approach to 2-Formylpyrroles: Synthesis of Magnolamide, Lobechine and Funebral
Yuen, Tsz-Ying,Eaton, Samantha E.,Woods, Tom M.,Furkert, Daniel P.,Choi, Ka Wai,Brimble, Margaret A.
, p. 1431 - 1437 (2015/10/05)
A convenient synthesis of the traditional medicine constituents magnolamide, lobechine and funebral is described. Construction of the 2-formylpyrrole core of these natural products was achieved by means of a Maillard reaction, involving condensation of the sugar surrogate, dihydropyranone 9, with the requisite primary amines. This approach offers a very direct and general route to the 2-formylpyrrole ring system. The synthesis of the 2-formylpyrrole core found in the traditional medicine constituents, magnolamide, lobechine and funebral, was constructed by a Maillard reaction, involving condensation of the sugar surrogate, dihydropyranone 9, with the requisite primary amines. This approach offers a very direct and general route to the 2-formylpyrrole ring system.
