911124-04-4

Basic information

• Product Name: 4-(aMinoMethyl)-2-fluoro-6-iodoaniline
• Synonyms: 4-(aMinoMethyl)-2-fluoro-6-iodoaniline
• CAS NO: 911124-04-4
• Molecular Formula: C₇H₈FIN₂
• Molecular Weight: 266.0546932
• Mol File: 911124-04-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(aMinoMethyl)-2-fluoro-6-iodoaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(aMinoMethyl)-2-fluoro-6-iodoaniline(911124-04-4)
• EPA Substance Registry System: 4-(aMinoMethyl)-2-fluoro-6-iodoaniline(911124-04-4)

Safety Data

• Hazardous Substances Data: 911124-04-4(Hazardous Substances Data)

Upstream product

• 849353-46-4 4-amino-3-fluoro-5-iodo-benzonitrile 

Relevant articles and documents

Novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and a pharmaceutical composition containing the same

This present invention relates to compounds of formula (I), in which R3 represents C2-C5 alkenyl or C2-C5 alkynyl and the other variables are as defined in the claims, isomers thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonists; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating pain, inflammatory disease of the joints, urinary bladder hypersensitivity including urinary incontinence, stomach duodenal ulcer, irritable bowel syndrome, inflammatory bowel disease, neurotic/allergic/inflammatory skin disease, psoriasis, asthma, chronic obstructive pulmonary disease, pruritus or prurigo.

NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receotor 1; VR1; TRPV1 )antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, and heart disease.