911141-79-2

Upstream product

• 312611-42-0 1-chloro-3-((1S,2R)-2-nitrocyclohexyl)benzene 

Downstream Products

• 911141-89-4 2-(4-Bromomethyl-benzoyl)-cyclopentanecarboxylic acid {(S)-1-[(1R,2S)-2-(3-chloro-phenyl)-cyclohexylcarbamoyl]-3-methyl-butyl}-amide 

Relevant academic research and scientific papers

CDK2/cyclinA inhibitors: Targeting the cyclinA recruitment site with small molecules derived from peptide leads

The syntheses of potent small molecule inhibitors of the CDK2/cyclinA recruitment site are described. Structure-activity trends of nanomolar octapeptides were examined through amino-acid substitution and truncation of the sequence resulting in the identif