911237-14-4

Upstream product

• 911236-83-4 (3S,4R,5S)-4-[(1S,2R)-2-Benzyloxy-1-(2-benzyloxy-ethyl)-pent-4-enyloxy]-5-(tert-butyl-dimethyl-silanyloxy)-3-methyl-oct-7-enenitrile 
• 947619-70-7 (S)-2-(4-methoxybenzyloxy)pent-4-enal 
• 911237-04-2 (2S)-2-(4-methoxybenzyloxy)-4-pentenol 
• 911237-06-4 (2S,3R,4S)-4-(4-Methoxy-benzyloxy)-2-methyl-hept-6-ene-1,3-diol 
• 911236-81-2 (4S,5R)-5-Allyl-4-[(1R,2S)-2-hydroxy-1-((S)-2-hydroxy-1-methyl-ethyl)-pent-4-enyloxy]-dihydro-furan-2-one 
• 911237-03-1 (R)-4-Isopropyl-3-[(S)-2-(4-methoxy-benzyloxy)-pent-4-enoyl]-oxazolidin-2-one 
• 911237-07-5 (2S,3R,4S)-4-(4-Methoxy-benzyloxy)-2-methyl-1-triisopropylsilanyloxy-hept-6-en-3-ol 
• 911237-08-6 [(1R,2S)-2-(4-Methoxy-benzyloxy)-1-((S)-1-methyl-2-triisopropylsilanyloxy-ethyl)-pent-4-enyloxy]-acetic acid 
• 911237-05-3 (2R,3R,4S)-1-((R)-4-Benzyl-2-thioxo-thiazolidin-3-yl)-3-hydroxy-4-(4-methoxy-benzyloxy)-2-methyl-hept-6-en-1-one 
• 911236-80-1 (S)-4-Hydroxy-3-[(1R,2S)-2-(4-methoxy-benzyloxy)-1-((S)-1-methyl-2-triisopropylsilanyloxy-ethyl)-pent-4-enyloxy]-butyronitrile 
• 911237-10-0 (4S,5R)-5-Allyl-4-{(1R,2S)-2-(tert-butyl-dimethyl-silanyloxy)-1-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-pent-4-enyloxy}-dihydro-furan-2-one 
• 911237-11-1 (3S,4R)-3-{(1R,2S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-pent-4-enyloxy}-hept-6-ene-1,4-diol 
• 911236-82-3 C₄₁H₆₈O₅Si₂ 
• 911237-12-2 (2S,3R,4S)-3-[(1S,2R)-2-Benzyloxy-1-(2-benzyloxy-ethyl)-pent-4-enyloxy]-4-(tert-butyl-dimethyl-silanyloxy)-2-methyl-hept-6-en-1-ol 

Downstream Products

• 911237-15-5 [(4S,5R,6S)-5-[(1S,2R)-2-Benzyloxy-1-(2-benzyloxy-ethyl)-pent-4-enyloxy]-6-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-4-methyl-non-8-enyl]-phosphonic acid dimethyl ester 
• 911236-84-5 {(S)-4-[(Z)-(2R,3S,8R,9S)-8-Benzyloxy-9-(2-benzyloxy-ethyl)-3-(tert-butyl-dimethyl-silanyloxy)-2,3,4,7,8,9-hexahydro-oxonin-2-yl]-2-oxo-pentyl}-phosphonic acid dimethyl ester 
• 911237-16-6 [(4S,5R,6S)-5-[(1S,2R)-2-Benzyloxy-1-(2-benzyloxy-ethyl)-pent-4-enyloxy]-6-(tert-butyl-dimethyl-silanyloxy)-4-methyl-2-oxo-non-8-enyl]-phosphonic acid dimethyl ester 
• 911236-91-4 C₄₁H₅₈O₈ 
• 911236-90-3 C₄₂H₆₀O₉ 
• 911236-89-0 C₅₀H₆₈O₁₀ 
• 911236-86-7 C₆₄H₁₀₀O₉Si₂ 
• 911236-85-6 5-[8-benzyloxy-9-(2-benzyloxy-ethyl)-3-(tert-butyl-dimethyl-silanyloxy)-2,3,4,7,8,9-hexahydro-oxonin-2-yl]-1-[3-hydroxy-7-(4-methoxy-benzyloxy)-3,5-dimethyl-8-(2-triisopropylsilanyloxy-ethyl)-oxocan-2-yl]-hex-1-en-3-one 
• 911236-87-8 2-{2-[8-benzyloxy-9-(2-benzyloxy-ethyl)-3-(tert-butyl-dimethyl-silanyloxy)-2,3,4,7,8,9-hexahydro-oxonin-2-yl]-propyl}-7-(4-methoxy-benzyloxy)-9,10a-dimethyl-6-(2-triisopropylsilanyloxy-ethyl)-octahydro-1,5-dioxa-benzocycloocten-3-one 
• 911236-88-9 2-{2-[8-benzyloxy-9-(2-benzyloxy-ethyl)-3-(tert-butyl-dimethyl-silanyloxy)-2,3,4,7,8,9-hexahydro-oxonin-2-yl]-propyl}-7-(4-methoxy-benzyloxy)-9,10a-dimethyl-6-(2-triisopropylsilanyloxy-ethyl)-octahydro-1,5-dioxa-benzocycloocten-3-one 

Relevant academic research and scientific papers

Enantioselective total synthesis of brevetoxin A: convergent coupling strategy and completion

A highly convergent, enantioselective total synthesis of brevetoxin A is reported. The development of a [X+ 2+ X] Horner-Wadsworth-Emmons/ cyclodehydration/reductive etherification convergent coupling strategy allowed a unified approach to the synthesis o

Improved synthesis of the ABCDE fragment of brevetoxin A

A second-generation synthesis of the BCDE fragment of brevetoxin A is described. Novel reactions were developed that extend the utility of the asymmetric glycolate alkylation reaction and improve scale-up to provide gram quantities of the B and E subunits