911285-92-2

Upstream product

• 911285-91-1 1-[6-benzoyloxy-2,4-bis(benzyloxy)-3-iodophenyl]-2-(4-benzyloxy-3-methoxyphenyl)-3,3-dimethoxypropan-1-one 

Downstream Products

• 911285-93-3 5,7,4'-tris(benzyloxy)-6-(3-hydroxy-3-methyl-1-butynyl)-3'-methoxyisoflavone 
• 85966-81-0 5,7,4'-trihydroxy-6-(3-methyl-2-butenyl)-3'-methoxyisoflavone 
• 911285-95-5 7,4'-bis(benzoyloxy)-6-(3-hydroxy-3-methylbutyl)-3'-methoxy-5-tosyloxyisoflavone 
• 911285-96-6 7,4'-bis(benzoyloxy)-6-(3-methyl-2-butenyl)-3'-methoxy-5-tosyloxyisoflavone 
• 911285-94-4 7,4'-bis(benzoyloxy)-5-hydroxy-6-(3-hydroxy-3-methylbutyl)-3'-methoxyisoflavone 
• 911412-05-0 7,4'-bis(benzoyloxy)-5-hydroxy-6-(3-methyl-2-butenyl)-3'-methoxyisoflavone 
• 911285-87-5 5,7,4'-trihydroxy-6-(3-hydroxy-3-methylbutyl)-3'-methoxyisoflavone 

Relevant academic research and scientific papers

Microwave-assisted regioselective synthesis of natural 6-prenylpolyhydroxyisoflavones and their hydrates with hypervalent iodine reagents

Microwave-assisted oxidative rearrangement of 3′-iodotetraalkoxychalcones with hypervalent iodine such as [hydroxy(tosyloxy)iodo]benzene or [bis(trifluoroacetoxy)iodo]benzene, followed by microwave-mediated hydrolysis and in situ cyclization of the resultant acetals gave 6-iodotrialkoxyisoflavones. Pd(0)-catalyzed coupling reaction of the 6-iodoisoflavones with 2-methyl-3-butyn-2-ol under microwave irradiation gave 6-alkynylisoflavones, whose hydrogenation gave the respective hydrates of wighteone, lupisoflavone and derrubone. Wighteone (1a), lupisoflavone (1b) and derrubone (1c) were obtained by dehydration of their respective hydrates under microwave irradiation.