91129-91-8

Usage

Molecular weight

230.23 g/mol

Chemical structure

A derivative of 1,2,3-triazole with a 5-methyl-1-phenyl group and a hydrazide functional group

Applications

a. Chemical and pharmaceutical applications
b. Building block for the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals
c. Research and development for the production of new organic compounds with potential therapeutic properties

Biological activity

Potential biological activity, making it a valuable compound in the field of organic chemistry

Versatility

Wide range of applications in various industries due to its unique chemical structure and properties

Upstream product

• 27049-64-5 5-methyl-1-phenyl-1H-1,2,3-triazole-4-carboxylic acid ethyl ester 

Downstream Products

• 342006-07-9 C₁₇H₁₅ClN₆OS 
• 950234-92-1 2-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-5-phenyl-1,3,4-oxadiazole 
• 1333229-33-6 C₂₀H₁₇N₅O 
• 1333229-29-0 C₁₅H₁₅N₅O 
• 342006-20-6 5-(5-methyl-1-phenyl-1H-[1,2,3]triazol-4-yl)-4-(3-trifluoromethyl-phenyl)-2,4-dihydro-[1,2,4]triazole-3-thione 
• 342006-15-9 4-(2-bromo-phenyl)-5-(5-methyl-1-phenyl-1H-[1,2,3]triazol-4-yl)-2,4-dihydro-[1,2,4]triazole-3-thione 
• 342006-17-1 4-(2-methoxy-phenyl)-5-(5-methyl-1-phenyl-1H-[1,2,3]triazol-4-yl)-2,4-dihydro-[1,2,4]triazole-3-thione 

Relevant academic research and scientific papers

Synthesis of 5-(1,2,3-Triazol-4-yl)-1,3,4-Oxa(thia) diazol-2-Amines as Antimicrobial Agents

AN EFFICIENT method for the synthesis of new 1,2,3-triazol-4-yl-1,3,4-oxadiazol-2-amines (4a-c) from phenyliso-thiocyanate and 1,2,3-triazolyl-4-hydrazides (3a-c) through cyclo-desulfurization in the presence of sodium acetate is reported. Also, cyclization of 3a-c with concentrated H2SO4 afforded the corresponding triazol-4-ylthiadiazoles)6a-c(. The new products were screened for their antimicrobial activities, and compounds; 4a-c showed excellent antimicrobial activities compared with the reference drugs. Also, the minimum inhibitory concentration (MIC) against the tested organisms was determined in which, compounds 2c and 4a showed the lowest MIC.

Synthesis and characterization of some new 1,2,4-triazines containing 1,2,3-triazole

A series of 3-(1 -aryl-1 H-1,2,3-triazol-4-yl)-6-phenyl-1,2,4-triazines were synthesized by the reaction of 1-aryl-1tf-1,2,3-triazole-4-carbohydrazide with 2-bromo-1- phenylethanone and sodium acetate in refluxed EtOH and AcOH. Their structures were chara