911304-65-9Relevant academic research and scientific papers
Synthesis and evaluation of thiazepines as interleukin-1β converting enzyme (ICE) inhibitors
Ellis, Christopher D.,Oppong, Kofi A.,Laufersweiler, Michael C.,O'Neil, Steven V.,Soper, David L.,Wang, Yili,Wos, John A.,Fancher, Amy N.,Lu, Wei,Suchanek, Maureen K.,Wang, Richard L.,De, Biswanath,Demuth Jr., Thomas P.
, p. 4728 - 4732 (2007/10/03)
A series of monocyclic thiazepine inhibitors of interleukin-1β converting enzyme (ICE) were synthesized in eight steps from commercially available intermediates. In vitro biological evaluation showed the thiazepines to be moderately potent ICE inhibitors,
