911319-72-7

Upstream product

• 4363-94-4 6-methoxyquinoline-4-carbaldehyde 
• 104311-79-7 trans-1-benzoyloxy-4-bromobut-2-ene 
• 911319-66-9 (1R,2R)-6-benzyloxy-2-tert-butoxycarbonylamino-3-oxo-1-(6-methoxyquinol-4-yl)-1-triethylsilyloxy-hexane 
• 911319-68-1 (1R,2S,3S)-3-acetoxy-2-tert-butoxycarbonylamino-1-(6-methoxyquinol-4-yl)-1-triethylsilyloxy-hexan-6-ol 
• 911319-64-7 (2R,3R)-2-((1R,2S)-2-Hydroxy-1,2-diphenyl-ethylamino)-3-(6-methoxy-quinolin-4-yl)-3-triethylsilanyloxy-propionic acid methyl ester 
• 911319-42-1 (3R,5R,6S)-3-[(R)-Hydroxy-(6-methoxy-quinolin-4-yl)-methyl]-2-oxo-5,6-diphenyl-morpholine-4-carboxylic acid benzyl ester 
• 911319-63-6 (3R,5R,6S)-3-[(R)-(6-Methoxy-quinolin-4-yl)-triethylsilanyloxy-methyl]-5,6-diphenyl-morpholin-2-one 
• 911319-48-7 (2S,3S)-3-acetoxy-N-tert-butoxycarbonyl-2-[(R)-6-methoxyquinol-4-yl-triethylsilyloxy]methyl-piperidine 
• 911319-69-2 (2S,3S)-N-tert-butoxycarbonyl-3-hydroxy-2-[(R)-6-methoxyquinol-4-yl-triethylsilyloxy]methyl-piperidine 
• 911319-49-8 6-Methoxy-4-[(R)-triethylsilanyloxy-((2S,3S)-3-trimethylsilanyloxy-piperidin-2-yl)-methyl]-quinoline 
• 911319-44-3 (2R,3R)-2-tert-Butoxycarbonylamino-3-(6-methoxy-quinolin-4-yl)-3-triethylsilanyloxy-propionic acid methyl ester 
• 911319-65-8 (2R,3R)-2-tert-butoxycarbonylamino-3-(6-methoxyquinol-4-yl)-3-triethylsilyloxy-propanal 
• 911319-70-5 trans-1-iodo-4-benzoyloxy-2-butene 
• 911319-51-2 (2R)-1-[(E)-4-benzoyloxy-2-butenyl]-2-[(R)-6-methoxyquinol-4-yl-triethylsilyloxy]methyl-3-oxo-piperidine 

Relevant academic research and scientific papers

Synthetic studies on quinine: Quinuclidine construction via a ketone enolate regio- and diastereoselective Pd-mediated allylic alkylation

7-Hydroxy-quinine was synthesized by an asymmetric aldol reaction that establishes the C8 and C9 stereochemistry, followed by construction of the 3-vinyl-quinuclidine azabicyclo[2.2.2]octane by C3-C4 ring closure using an intramolecular palladium-mediated