91132-62-6Relevant academic research and scientific papers
One-pot synthesis of 6,11-dihydro-5H-indolizino[8,7-b]indoles via sequential formation of β-enamino ester, Michael addition and Pictet-Spengler reactions
Zhu, Dan,Sun, Jing,Yan, Chao-Guo
, p. 62817 - 62826 (2014)
β-Enamino esters generated from addition of tryptamines to alkyl propiolates reacted with 3-phenacylideneoxindoles in the presence of anhydrous ZnCl2 to give functionalized 2-pyrrolo-3′-yloxindoles in satisfactory yields, which can be further c
Three-Component Synthesis of Quinolines Based on Radical Cascade Visible-Light Photoredox Catalysis
Choi, Jun-Ho,Park, Cheol-Min
supporting information, p. 3553 - 3562 (2018/09/22)
Synthesis of highly substituted quinolines has been developed based on three-component radical cascade based on visible-light photoredox catalysis. This tandem coupling reaction has been coordinated to proceed with high chemoselectivity based on the differential electronic properties of coupling partners. Subjection of electron-rich β-aminoacrylates with electron-deficient halides and alkenes to the optimized conditions leads to the formation of quinolines in good yields after in situ oxidation of tetrahydroquinolines. Detailed mechanistic studies which reveal an unexpected reaction pathway is described. (Figure presented.).
A facile one-pot domino reaction for the stereoselective synthesis of acryl derivatives promoted by Ca(OTf)2
Yaragorla, Srinivasarao,Saini, Pyare Lal,Pareek, Abhishek,Almansour, Abdulrahman I.,Arumugam, Natarajan
supporting information, p. 2034 - 2038 (2016/04/26)
A facile one-pot domino reaction for the stereoselective synthesis of acryl derivatives has been reported using alkaline earth catalyst [Ca(OTf)2]. Initially aryl amine reacts with ethyl propiolate to form β-enamino ester which further reacts w
Povarov reaction of β-enamino esters and isatin-3-imines for diastereoselective synthesis of spiro[indoline-3,2′-quinolines]
Gao, Hong,Sun, Jing,Yan, Chao-Guo
, p. 489 - 495 (2014/03/21)
The p-toluenesulfonic acid catalyzed Povarov reaction of isatin-3-imines with β-enamino esters, which were generated in situ from the reaction of arylamines and methyl propiolate in ethanol, afforded the polysubstituted spiro[indoline-3,2′-quinolines] in
Domino reaction of arylamine, methyl propiolate, aromatic aldehyde, and indole for facile synthesis of functionalized indol-3-yl acrylates
Zhang, Li-Li,Sun, Jing,Yan, Chao-Guo
, p. 6965 - 6967 (2013/01/15)
In the presence of FeCl3 as catalyst the one-pot domino reactions of arylamines, methyl propiolate, aromatic aldehydes, and indole in ethanol at room temperature proceeded smoothly to give methyl 2-(1H-indol-3-yl)arylmethyl-3-arylamino)acrylate
Synthesis of functionalized 2-aminohydropyridines and 2-pyridinones via domino reactions of arylamines, methyl propiolate, aromatic aldehydes, and substituted acetonitriles
Sun, Jing,Sun, Yan,Xia, Er-Yan,Yan, Chao-Guo
experimental part, p. 436 - 441 (2011/10/08)
An efficient and practical synthetic method for the functionalized 2-amino hydropyridines and 2-pyridinones was successfully developed via the domino reactions of arylamines, methyl propiolate, aromatic aldehydes and the substituted acetonitriles with tri
