91134-17-7Relevant academic research and scientific papers
Enantioselective synthesis of α-hydroxyacids through oxidation of terminal alkenes with AD-mix/TEMPO
Javier Aladro,Guerra, Francisco M.,Javier Moreno-Dorado,Bustamante, Jesús M.,Jorge, Zacarías D.,Massanet, Guillermo M.
, p. 3209 - 3213 (2000)
α-Hydroxyacids can be enantioselectively prepared by means of a two- step oxidation process, involving first the asymmetric dihydroxylation of a terminal alkene and subsequent oxidation with TEMPO/NaOCl/NaClO2 in good to excellent yields. No fragmentation of the glycol intermediate was detected. (C) 2000 Elsevier Science Ltd.
