91135-40-9

Usage

Type of compound

Nitrile derivative of naphthalene

Amino group position

3-position

Common uses

Intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes

Appearance

White to pale yellow solid

Solubility

Soluble in organic solvents

Handling precautions

Can be harmful if ingested, inhaled, or if it comes into contact with the skin.

Upstream product

• 129667-51-2 4-Amino-3-nitronaphthalene-1-carbonitrile 
• 1016-17-7 3-Nitronaphthalene-1-carbonitrile 

Relevant academic research and scientific papers

Dissociation of naphthoic acids in non-aqueous media. Comparison of benzene and naphthalene skeletons

Seven monosubstituted 1-naphthoic acids were synthesized by new or modified procedures, and their dissociation constants were measured potentiometrically at 25 °C in methanol, acetonitrile, dimethylformamide, and pyridine. Dissociation constants of these along with thirteen substituted 1-naphthoic acids and twenty-five substituted 2-naphthoic acids previously studied were measured at 25 °C in ethanol and dimethyl sulfoxide. The pKHA values of 3-and 4-substituted 1-naphthoic acids were treated by simple linear regression and principal component analysis, and the results were used for comparison of model compounds and of corresponding 3-and 4-substituted benzoic acids with the aim of comparison of benzene and naphthalene skeletons. It has been found, the 3 and 4 positions of the 1-naphthyl system can roughly be compared with the meta and para positions of benzene, respectively.