911361-47-2Relevant academic research and scientific papers
InCl3 catalyzed carbene insertion into O-H bonds: Efficient synthesis of ethers
Radha Krishna, Palakodety,Prapurna, Y. Lakshmi,Alivelu, Munagala
, p. 3460 - 3462 (2011)
An efficient InCl3 mediated insertion of the carbene fragment (:CHCO2Et), generated in situ from ethyl diazoacetate into O-H bond of a series of saturated and unsaturated alcohols under mild conditions has been developed to afford the corresponding ethers as exclusive products in good to high yields (70-95%) and in shorter reaction times. In the case of unsaturated alcohols, the reaction proceeded with unprecedented selectivity resulting in ethers as the only products and in high yields.
